Experimental Babesia bovis infection in Holstein calves.

Journal Article (Journal Article)

One intact and two splenectomized Holstein calves were infected intravenously with a Mexican strain of Babesia bovis and killed following the onset of severe clinical disease. A light and electron microscopic study was conducted on selected tissues to examine the relationship between parasitized erythrocytes and microvascular endothelial cells. The pattern and degree of specific organ sequestration of parasitized erythrocytes was assessed and correlated to lesions. Red blood cells infected with Babesia bovis exhibited stellate membrane protrusions. This morphological change appeared to mediate erythrocyte sequestration in the microvascular and capillary beds of the brain, kidney, and adrenal gland by an as yet unknown mechanism(s).

Full Text

Duke Authors

Cited Authors

  • Everitt, JI; Shadduck, JA; Steinkamp, C; Clabaugh, G

Published Date

  • September 1986

Published In

Volume / Issue

  • 23 / 5

Start / End Page

  • 556 - 562

PubMed ID

  • 3776013

International Standard Serial Number (ISSN)

  • 0300-9858

Digital Object Identifier (DOI)

  • 10.1177/030098588602300503


  • eng

Conference Location

  • United States