Assembly of type C oncornaviruses: a model.

Journal Article (Journal Article)

The salient features of this model for oncornavirus assembly are that uncleaved precursor molecules to the internal virus polypeptides possess specific recognition sites both for viral envelope constituents already inserted in the cell membrane and for the viral RNA. After orderly alignment of these components at the budding site, virus maturation proceeds through specific proteolytic cleavage of the precursor components and association of the resultant molecules into the characteristic type C virion substructures revealed by electron microscopy.

Full Text

Duke Authors

Cited Authors

  • Bolognesi, DP; Montelaro, RC; Frank, H; Schäfer, W

Published Date

  • January 13, 1978

Published In

Volume / Issue

  • 199 / 4325

Start / End Page

  • 183 - 186

PubMed ID

  • 202022

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.202022


  • eng

Conference Location

  • United States