The long-term treatment of panic disorder.

Journal Article (Journal Article;Review)

Panic disorder is a chronic and recurring condition, and there is therefore a need for long-term therapy. This paper reviews data from long-term studies of drug treatment for panic disorder to address issues of whether medication benefits persist, whether improvement can continue over several months or years, the tolerability of long-term treatment, patient selection for long-term treatment, and when and how to stop medication. The main conclusion is that long-term drug treatment of panic disorder is necessary, effective, and safe. Serotonin selective reuptake inhibitors offer benefits of ease of dosing, good tolerability, and no safety or dependence problems; TCAs are often poorly tolerated, and benzodiazepines are associated with dependence problems. Withdrawal from all types of medication should be considered, slow, planned, and individualized; some patients require an indefinite duration of treatment.

Full Text

Duke Authors

Cited Authors

  • Davidson, JR

Published Date

  • January 1, 1998

Published In

Volume / Issue

  • 59 Suppl 8 /

Start / End Page

  • 17 - 21

PubMed ID

  • 9707158

International Standard Serial Number (ISSN)

  • 0160-6689


  • eng

Conference Location

  • United States