A comparative evaluation of three discriminant scales for endogenous depression.

Journal Article (Journal Article)

Three discriminant scales for diagnosing endogenous depression were examined in 56 depressed inpatients. These scales were the Newcastle 1 (N1), Newcastle 2 (N2), and Michigan Index (MI). The scales agreed on diagnosis in 17 (30%) patients; respective frequencies of endogenous depression were 23%, 57%, and 78% for the N2, N1, and MI scales. Relationships were examined between treatment response to isocarboxazid, drug dose, and diagnostic type for each scale. Significant dose X diagnosis interactions were noted for N1 and N2, but not for MI. A correlational within-dose analysis of all three scales revealed that actual diagnostic score was related to outcome only for high-dose patients on the Newcastle-1 scale; no other significant correlations emerged.

Full Text

Duke Authors

Cited Authors

  • Davidson, JR; Pelton, S

Published Date

  • February 1, 1988

Published In

Volume / Issue

  • 23 / 2

Start / End Page

  • 193 - 200

PubMed ID

  • 3363027

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/0165-1781(88)90009-1


  • eng

Conference Location

  • Ireland