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The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms.

Publication ,  Journal Article
Addington, J; Liu, L; Perkins, DO; Carrion, RE; Keefe, RSE; Woods, SW
Published in: Schizophr Bull
January 2017

In the literature, there have been several attempts to develop prediction models for youth who are at clinical high risk (CHR) of developing psychosis. Although there are no specific clinical or demographic variables that seem to consistently predict the later transition to psychosis in those CHR youth, in addition to attenuated psychotic symptoms, the most commonly occuring predictors tend to be poor social functioning and certain cognitive tasks. Unfortunately, there has been little attempt to replicate alogorithms. A recently published article by Cornblatt et al suggested that, for individuals with attentuated psychotic symptoms (APS), disorganized communication, suspiciousness, verbal memory, and a decline in social functioning were the best predictors of later transition to psychosis (the RAP model). The purpose of this article was to first test the prediction model of Cornblatt et al with a new sample of individuals with APS from the PREDICT study. The RAP model was not the best fit for the PREDICT data. However, using other variables from PREDICT, it was demonstrated that unusual thought content, disorganized communication, baseline social functioning, verbal fluency, and memory, processing speed and age were predictors of later transition to psychosis in the PREDICT sample. Although the predictors were different in these 2 models, both supported that disorganized communication, poor social functioning, and verbal memory, were good candidates as predictors for later conversion to psychosis.

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Published In

Schizophr Bull

DOI

EISSN

1745-1701

Publication Date

January 2017

Volume

43

Issue

1

Start / End Page

57 / 63

Location

United States

Related Subject Headings

  • Young Adult
  • Social Behavior
  • Schizophrenia
  • Risk
  • Psychotic Disorders
  • Psychiatry
  • Prognosis
  • Prodromal Symptoms
  • Models, Statistical
  • Male
 

Citation

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ICMJE
MLA
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Addington, J., Liu, L., Perkins, D. O., Carrion, R. E., Keefe, R. S. E., & Woods, S. W. (2017). The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms. Schizophr Bull, 43(1), 57–63. https://doi.org/10.1093/schbul/sbw152
Addington, Jean, Lu Liu, Diana O. Perkins, Ricardo E. Carrion, Richard S. E. Keefe, and Scott W. Woods. “The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms.Schizophr Bull 43, no. 1 (January 2017): 57–63. https://doi.org/10.1093/schbul/sbw152.
Addington J, Liu L, Perkins DO, Carrion RE, Keefe RSE, Woods SW. The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms. Schizophr Bull. 2017 Jan;43(1):57–63.
Addington, Jean, et al. “The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms.Schizophr Bull, vol. 43, no. 1, Jan. 2017, pp. 57–63. Pubmed, doi:10.1093/schbul/sbw152.
Addington J, Liu L, Perkins DO, Carrion RE, Keefe RSE, Woods SW. The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms. Schizophr Bull. 2017 Jan;43(1):57–63.
Journal cover image

Published In

Schizophr Bull

DOI

EISSN

1745-1701

Publication Date

January 2017

Volume

43

Issue

1

Start / End Page

57 / 63

Location

United States

Related Subject Headings

  • Young Adult
  • Social Behavior
  • Schizophrenia
  • Risk
  • Psychotic Disorders
  • Psychiatry
  • Prognosis
  • Prodromal Symptoms
  • Models, Statistical
  • Male