Amphotericin B Resistant Apophysomyces elegans Causing Rhino-oculo-Cerebral Mucormycosis in an Immunocompetent Host.

Journal Article

Mucormycosis, an angioinvasive infection is caused by the ubiquitous filamentous fungi of the order Mucorales and class Mucormycetes. Reports of this disease are on the rise over the past few decades. Rhino-oculo-Cerebral presentation associated with uncontrolled diabetes is the predominant characteristic of this entity. We report here a case of rhinooculocerebral mucormycosis (ROCM) due to Apophysomyces elegans (A. elegans) in a 45-year-old diabetic lady with background illness of hypothyroidism and polyradiculoneuropathy. Though this condition is usually managed with surgical debridement of the affected tissue and medical therapy with Amphotericin B, the isolate recovered in our case was found to be resistant to Amphotericin B.

Full Text

Duke Authors

Cited Authors

  • Biswas, D; Kotwal, A; Kakati, B; Ahmad, S

Published Date

  • August 2015

Published In

Volume / Issue

  • 9 / 8

Start / End Page

  • DD01 - DD02

PubMed ID

  • 26435947

Pubmed Central ID

  • PMC4576538

Electronic International Standard Serial Number (EISSN)

  • 0973-709X

International Standard Serial Number (ISSN)

  • 2249-782X

Digital Object Identifier (DOI)

  • 10.7860/jcdr/2015/13929.6272


  • eng