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Seroprevalence of human parvovirus B19 in healthy blood donors.

Publication ,  Journal Article
Kumar, S; Gupta, RM; Sen, S; Sarkar, RS; Philip, J; Kotwal, A; Sumathi, SH
Published in: Medical journal, Armed Forces India
July 2013

Human parvovirus B19 is an emerging transfusion transmitted infection. Although parvovirus B19 infection is connected with severe complications in some recipients, donor screening is not yet mandatory. To reduce the risk of contamination, plasma-pool screening and exclusion of highly viraemic donations are recommended. In this study the prevalence of parvovirus B19 in healthy blood donors was detected by ELISA.A total of 1633 samples were screened for IgM and IgG antibodies against parvovirus B19 by ELISA. The initial 540 samples were screened for both IgM and IgG class antibodies and remaining 1093 samples were screened for only IgM class antibodies by ELISA.Net prevalence of IgM antibodies to human parvovirus B19 in our study was 7.53% and prevalence of IgG antibodies was 27.96%. Dual positivity (IgG and IgM) was 2.40%.The seroprevalence of human parvovirus B19 among blood donor population in our study is high, and poses an adverse transfusion risk especially in high-risk group of patients who have no detectable antibodies to B19. Studies with large sample size are needed to validate these results.

Duke Scholars

Published In

Medical journal, Armed Forces India

DOI

EISSN

2213-4743

ISSN

0377-1237

Publication Date

July 2013

Volume

69

Issue

3

Start / End Page

268 / 272

Related Subject Headings

  • General & Internal Medicine
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
 

Citation

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Kumar, S., Gupta, R. M., Sen, S., Sarkar, R. S., Philip, J., Kotwal, A., & Sumathi, S. H. (2013). Seroprevalence of human parvovirus B19 in healthy blood donors. Medical Journal, Armed Forces India, 69(3), 268–272. https://doi.org/10.1016/j.mjafi.2012.11.009
Kumar, Satish, R. M. Gupta, Sourav Sen, R. S. Sarkar, J. Philip, Atul Kotwal, and S. H. Sumathi. “Seroprevalence of human parvovirus B19 in healthy blood donors.Medical Journal, Armed Forces India 69, no. 3 (July 2013): 268–72. https://doi.org/10.1016/j.mjafi.2012.11.009.
Kumar S, Gupta RM, Sen S, Sarkar RS, Philip J, Kotwal A, et al. Seroprevalence of human parvovirus B19 in healthy blood donors. Medical journal, Armed Forces India. 2013 Jul;69(3):268–72.
Kumar, Satish, et al. “Seroprevalence of human parvovirus B19 in healthy blood donors.Medical Journal, Armed Forces India, vol. 69, no. 3, July 2013, pp. 268–72. Epmc, doi:10.1016/j.mjafi.2012.11.009.
Kumar S, Gupta RM, Sen S, Sarkar RS, Philip J, Kotwal A, Sumathi SH. Seroprevalence of human parvovirus B19 in healthy blood donors. Medical journal, Armed Forces India. 2013 Jul;69(3):268–272.
Journal cover image

Published In

Medical journal, Armed Forces India

DOI

EISSN

2213-4743

ISSN

0377-1237

Publication Date

July 2013

Volume

69

Issue

3

Start / End Page

268 / 272

Related Subject Headings

  • General & Internal Medicine
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences