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Validation of four definitions of melancholia by the dexamethasone suppression test.

Publication ,  Journal Article
Davidson, J; Lipper, S; Zung, WW; Strickland, R; Krishnan, R; Mahorney, S
Published in: Am J Psychiatry
October 1984

The authors evaluated four sets of diagnostic criteria, the Newcastle Index, DSM-III, RDC, and the Michigan Diagnostic Index, for the diagnosis of melancholia. Forty-nine depressed inpatients, all of whom met RDC for major depression, also received consensus diagnostic assessment for melancholia. The dexamethasone suppression test (DST) was administered before drug treatment began. Results showed that the sensitivity of the DST ranged from 39% to 48%, specificity from 80% to 100%, and diagnostic confidence from 66% to 100%. All four scales received validation, but DSM-III showed the lowest specificity and predictive value.

Duke Scholars

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

October 1984

Volume

141

Issue

10

Start / End Page

1220 / 1223

Location

United States

Related Subject Headings

  • Psychometrics
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Middle Aged
  • Manuals as Topic
  • Male
  • Hydrocortisone
  • Humans
  • Female
  • Evaluation Studies as Topic
 

Citation

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Davidson, J., Lipper, S., Zung, W. W., Strickland, R., Krishnan, R., & Mahorney, S. (1984). Validation of four definitions of melancholia by the dexamethasone suppression test. Am J Psychiatry, 141(10), 1220–1223. https://doi.org/10.1176/ajp.141.10.1220
Davidson, J., S. Lipper, W. W. Zung, R. Strickland, R. Krishnan, and S. Mahorney. “Validation of four definitions of melancholia by the dexamethasone suppression test.Am J Psychiatry 141, no. 10 (October 1984): 1220–23. https://doi.org/10.1176/ajp.141.10.1220.
Davidson J, Lipper S, Zung WW, Strickland R, Krishnan R, Mahorney S. Validation of four definitions of melancholia by the dexamethasone suppression test. Am J Psychiatry. 1984 Oct;141(10):1220–3.
Davidson, J., et al. “Validation of four definitions of melancholia by the dexamethasone suppression test.Am J Psychiatry, vol. 141, no. 10, Oct. 1984, pp. 1220–23. Pubmed, doi:10.1176/ajp.141.10.1220.
Davidson J, Lipper S, Zung WW, Strickland R, Krishnan R, Mahorney S. Validation of four definitions of melancholia by the dexamethasone suppression test. Am J Psychiatry. 1984 Oct;141(10):1220–1223.
Journal cover image

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

October 1984

Volume

141

Issue

10

Start / End Page

1220 / 1223

Location

United States

Related Subject Headings

  • Psychometrics
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Middle Aged
  • Manuals as Topic
  • Male
  • Hydrocortisone
  • Humans
  • Female
  • Evaluation Studies as Topic