Lipid-lowering Therapy in Patients With High Cardiovascular Risk: Dose or Combination?


Journal Article

Cardiovascular disease is the leading cause of death in the world. Dyslipidemia, manifested by elevated low-density lipoprotein cholesterol (LDL-C) levels, is central to the development and progression of atherosclerosis. Dyslipidemia has become a primary target of intervention in strategies for the prevention of cardiovascular events. Therapeutic lifestyle changes, such as increased physical activity, weight loss, smoking cessation, and adoption of a healthier diet, are effectively reducing cardiovascular risk in primary and secondary prevention. The combination therapy lowered LDL-C levels and achieved the LDL-C target in patients with high cardiovascular risk.

Full Text

Duke Authors

Cited Authors

  • Roever, L; Biondi-Zoccai, G; Rao, SV

Published Date

  • March 2017

Published In

Volume / Issue

  • 39 / 3

Start / End Page

  • 659 - 660

PubMed ID

  • 28190598

Pubmed Central ID

  • 28190598

Electronic International Standard Serial Number (EISSN)

  • 1879-114X

Digital Object Identifier (DOI)

  • 10.1016/j.clinthera.2017.01.029


  • eng

Conference Location

  • United States