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MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.

Publication ,  Journal Article
Lalla, RV; Bowen, J; Barasch, A; Elting, L; Epstein, J; Keefe, DM; McGuire, DB; Migliorati, C; Nicolatou-Galitis, O; Peterson, DE; Sonis, ST ...
Published in: Cancer
May 2014

Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis.A literature search was conducted to identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article was independently reviewed by 2 reviewers. Studies were rated according to the presence of major and minor flaws as per previously published criteria. The body of evidence for each intervention, in each treatment setting, was assigned a level of evidence, based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible.The literature search identified 8279 papers, 1032 of which were retrieved for detailed evaluation based on titles and abstracts. Of these, 570 qualified for final inclusion in the systematic reviews. Sixteen new guidelines were developed for or against the use of various interventions in specific treatment settings. In total, the MASCC/ISOO Mucositis Guidelines now include 32 guidelines: 22 for oral mucositis and 10 for gastrointestinal mucositis. This article describes these updated guidelines.The updated MASCC/ISOO Clinical Practice Guidelines for mucositis will help clinicians provide evidence-based management of mucositis secondary to cancer therapy.

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Published In

Cancer

DOI

EISSN

1097-0142

ISSN

0008-543X

Publication Date

May 2014

Volume

120

Issue

10

Start / End Page

1453 / 1461

Related Subject Headings

  • Sucralfate
  • Stomatitis
  • Radiotherapy
  • Radiation-Protective Agents
  • Protective Agents
  • Proctitis
  • Phototherapy
  • Oral Hygiene
  • Oncology & Carcinogenesis
  • Neoplasms
 

Citation

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Lalla, R. V., Bowen, J., Barasch, A., Elting, L., Epstein, J., Keefe, D. M., … Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO), . (2014). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer, 120(10), 1453–1461. https://doi.org/10.1002/cncr.28592
Lalla, Rajesh V., Joanne Bowen, Andrei Barasch, Linda Elting, Joel Epstein, Dorothy M. Keefe, Deborah B. McGuire, et al. “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.Cancer 120, no. 10 (May 2014): 1453–61. https://doi.org/10.1002/cncr.28592.
Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014 May;120(10):1453–61.
Lalla, Rajesh V., et al. “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.Cancer, vol. 120, no. 10, May 2014, pp. 1453–61. Epmc, doi:10.1002/cncr.28592.
Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, Migliorati C, Nicolatou-Galitis O, Peterson DE, Raber-Durlacher JE, Sonis ST, Elad S, Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014 May;120(10):1453–1461.
Journal cover image

Published In

Cancer

DOI

EISSN

1097-0142

ISSN

0008-543X

Publication Date

May 2014

Volume

120

Issue

10

Start / End Page

1453 / 1461

Related Subject Headings

  • Sucralfate
  • Stomatitis
  • Radiotherapy
  • Radiation-Protective Agents
  • Protective Agents
  • Proctitis
  • Phototherapy
  • Oral Hygiene
  • Oncology & Carcinogenesis
  • Neoplasms