Cardiac Dysfunction and Heart Failure in Hematopoietic Cell Transplantation Survivors: Emerging Paradigms in Pathophysiology, Screening, and Prevention.


Journal Article (Review)

Hematopoietic cell transplantation (HCT) has been used for curative intent in patients with hematologic and nonhematologic malignancies, resulting in an increasing number of HCT survivors. These survivors are at risk for serious and life-threatening complications, including cardiovascular disease (CVD). This article provides an overview of CVD in HCT survivors, describing the pathophysiology of disease, with a special emphasis on therapeutic exposures and comorbidities unique to this population. This article also discusses novel screening and prevention strategies that have shown promise in non-HCT cancer populations, emphasizing opportunities for collaboration between cardiologists and hematologists to improve the cardiovascular health of HCT survivors.

Full Text

Duke Authors

Cited Authors

  • Armenian, SH; Ryan, TD; Khouri, MG

Published Date

  • April 2017

Published In

Volume / Issue

  • 13 / 2

Start / End Page

  • 337 - 345

PubMed ID

  • 28279419

Pubmed Central ID

  • 28279419

International Standard Serial Number (ISSN)

  • 1551-7136

Digital Object Identifier (DOI)

  • 10.1016/j.hfc.2016.12.008


  • eng

Conference Location

  • United States