NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1.2017.

Journal Article (Journal Article)

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are different manifestations of the same disease and managed in much the same way. The advent of novel CD20 monoclonal antibodies led to the development of effective chemoimmunotherapy regimens. More recently, small molecule inhibitors targeting kinases involved in a number of critical signaling pathways and a small molecule inhibitor of the BCL-2 family of proteins have demonstrated activity for the treatment of patients with CLL/SLL. These NCCN Guidelines Insights highlight important updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for CLL/SLL for the treatment of patients with newly diagnosed or relapsed/refractory CLL/SLL.

Full Text

Duke Authors

Cited Authors

  • Wierda, WG; Zelenetz, AD; Gordon, LI; Abramson, JS; Advani, RH; Andreadis, CB; Bartlett, N; Byrd, JC; Caimi, P; Fayad, LE; Fisher, RI; Glenn, MJ; Habermann, TM; Harris, NL; Hernandez-Ilizaliturri, F; Hoppe, RT; Horwitz, SM; Kaminski, MS; Kelsey, CR; Kim, YH; Krivacic, S; LaCasce, AS; Martin, MG; Nademanee, A; Porcu, P; Press, O; Rabinovitch, R; Reddy, N; Reid, E; Roberts, K; Saad, AA; Snyder, ED; Sokol, L; Swinnen, LJ; Vose, JM; Yahalom, J; Dwyer, MA; Sundar, H

Published Date

  • March 2017

Published In

Volume / Issue

  • 15 / 3

Start / End Page

  • 293 - 311

PubMed ID

  • 28275031

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2017.0030


  • eng

Conference Location

  • United States