Screening and management of adverse endocrine outcomes in adult survivors of childhood and adolescent cancer.

Journal Article (Journal Article;Review)

5 year survival for childhood and adolescent cancer in developed countries is now in excess of 80% and the number of survivors of cancer continues to increase worldwide. After completion of therapy, many of these survivors will face a lifelong risk of endocrine late effects. We summarise the available evidence related to the prevalence and risk factors for endocrine late effects among adult survivors of childhood and adolescent cancer. Present screening, surveillance, and treatment recommendations differ by country and region, so we also highlight the continued effort to harmonise the international guidelines for this population.

Full Text

Duke Authors

Cited Authors

  • Tonorezos, ES; Hudson, MM; Edgar, AB; Kremer, LC; Sklar, CA; Wallace, WHB; Oeffinger, KC

Published Date

  • July 2015

Published In

Volume / Issue

  • 3 / 7

Start / End Page

  • 545 - 555

PubMed ID

  • 25873569

Pubmed Central ID

  • PMC4490990

Electronic International Standard Serial Number (EISSN)

  • 2213-8595

Digital Object Identifier (DOI)

  • 10.1016/S2213-8587(15)00038-8


  • eng

Conference Location

  • England