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Contributions of the hippocampus to feedback learning.

Publication ,  Journal Article
Dickerson, KC; Delgado, MR
Published in: Cognitive, affective & behavioral neuroscience
December 2015

Humans learn about the world in a variety of manners, including by observation, by associating cues in the environment, and via feedback. Across species, two brain structures have been predominantly involved in these learning processes: the hippocampus--supporting learning via observation and paired association--and the striatum--critical for feedback learning. This simple dichotomy, however, has recently been challenged by reports of hippocampal engagement in feedback learning, although the role of the hippocampus is not fully understood. The purpose of this experiment was to characterize the hippocampal response during feedback learning by manipulating varying levels of memory interference. Consistent with prior reports, feedback learning recruited the striatum and midbrain. Notably, feedback learning also engaged the hippocampus. The level of activity in these regions was modulated by the degree of memory interference, such that the greatest activation occurred during the highest level of memory interference. Importantly, the accuracy of information learned via feedback correlated with hippocampal activation and was reduced by the presence of high memory interference. Taken together, these findings provide evidence of hippocampal involvement in feedback learning by demonstrating both its relevance for the accuracy of information learned via feedback and its susceptibility to interference.

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Published In

Cognitive, affective & behavioral neuroscience

DOI

EISSN

1531-135X

ISSN

1530-7026

Publication Date

December 2015

Volume

15

Issue

4

Start / End Page

861 / 877

Related Subject Headings

  • Young Adult
  • Visual Perception
  • Probability Learning
  • Neuropsychological Tests
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Hippocampus
  • Female
 

Citation

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Dickerson, K. C., & Delgado, M. R. (2015). Contributions of the hippocampus to feedback learning. Cognitive, Affective & Behavioral Neuroscience, 15(4), 861–877. https://doi.org/10.3758/s13415-015-0364-5
Dickerson, Kathryn C., and Mauricio R. Delgado. “Contributions of the hippocampus to feedback learning.Cognitive, Affective & Behavioral Neuroscience 15, no. 4 (December 2015): 861–77. https://doi.org/10.3758/s13415-015-0364-5.
Dickerson KC, Delgado MR. Contributions of the hippocampus to feedback learning. Cognitive, affective & behavioral neuroscience. 2015 Dec;15(4):861–77.
Dickerson, Kathryn C., and Mauricio R. Delgado. “Contributions of the hippocampus to feedback learning.Cognitive, Affective & Behavioral Neuroscience, vol. 15, no. 4, Dec. 2015, pp. 861–77. Epmc, doi:10.3758/s13415-015-0364-5.
Dickerson KC, Delgado MR. Contributions of the hippocampus to feedback learning. Cognitive, affective & behavioral neuroscience. 2015 Dec;15(4):861–877.
Journal cover image

Published In

Cognitive, affective & behavioral neuroscience

DOI

EISSN

1531-135X

ISSN

1530-7026

Publication Date

December 2015

Volume

15

Issue

4

Start / End Page

861 / 877

Related Subject Headings

  • Young Adult
  • Visual Perception
  • Probability Learning
  • Neuropsychological Tests
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Hippocampus
  • Female