Systolic blood pressure goals to reduce cardiovascular disease among older adults.

Published

Journal Article

The 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8) was recently published. This guideline recommended that older adults (≥60 years) without diabetes or chronic kidney disease with systolic blood pressure (SBP) ≥150 mm Hg or diastolic blood pressure (DBP) ≥90 mm Hg be initiated on antihypertensive medication with a treatment goal SBP/DBP <150/90 mm Hg. In contrast, the previous 3 JNC guidelines recommended treatment for these individuals be initiated at SBP/DBP ≥140/90 mm Hg with goal SBP/DBP <140/90 mm Hg. In this article, we review randomized trials of antihypertensive medication and observational data on SBP and DBP with cardiovascular outcomes among older adults, possible explanations underlying the different findings from these randomized trials and observational studies, and contemporary antihypertensive treatment patterns among older U.S. adults. In closing, we highlight future research needs related to hypertension and outcomes among older adults.

Full Text

Duke Authors

Cited Authors

  • Muntner, P; Bowling, CB; Shimbo, D

Published Date

  • August 2014

Published In

Volume / Issue

  • 348 / 2

Start / End Page

  • 129 - 134

PubMed ID

  • 24978394

Pubmed Central ID

  • 24978394

Electronic International Standard Serial Number (EISSN)

  • 1538-2990

Digital Object Identifier (DOI)

  • 10.1097/MAJ.0000000000000314

Language

  • eng

Conference Location

  • United States