Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group.

Published

Journal Article (Review)

Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

Full Text

Duke Authors

Cited Authors

  • Tsalik, EL; Petzold, E; Kreiswirth, BN; Bonomo, RA; Banerjee, R; Lautenbach, E; Evans, SR; Hanson, KE; Klausner, JD; Patel, R; and the Diagnostics and Devices Committee, ; of the Antibacterial Resistance Leadership Group,

Published Date

  • March 2017

Published In

Volume / Issue

  • 64 / suppl_1

Start / End Page

  • S41 - S47

PubMed ID

  • 28350903

Pubmed Central ID

  • 28350903

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

International Standard Serial Number (ISSN)

  • 1058-4838

Digital Object Identifier (DOI)

  • 10.1093/cid/ciw831

Language

  • eng