Portable system for wide-field, sub-millimeter functional imaging of the morphological landscape of breast tumor margins


Conference Paper

© OSA 2016. We have developed a portable, breast margin assessment probe (BMAP) that surgeons can use to evaluate the breast tumor margin status during surgery. The approach presented here leverages a custom16-channel photodiode array raster-scanning-based system with precision pressure control (ΔP = 1mmHg) and compressive sensing with an optimized set of 8 wavelengths in the visible spectral range. A scalable Monte-Carlo model processes the sub-millimeter (0.75mm) resolution reflectance data, providing detailed optical parameter maps of breast margin morphology (specifically used is the fat to fibroglandular content ratio) over an area of ~ 2x2 cm2 in ~4 minutes.

Full Text

Duke Authors

Cited Authors

  • Nichols, BS; McCachren, SS; Palmer, GM; Ramanujam, N

Published Date

  • April 18, 2016

Published In

  • Optics Infobase Conference Papers

International Standard Book Number 13 (ISBN-13)

  • 9781943580101

Digital Object Identifier (DOI)

  • 10.1364/TRANSLATIONAL.2016.TM4B.6

Citation Source

  • Scopus