Antibiotic-loaded cement in total hip replacement: current indications, efficacy, and complications.

Journal Article (Journal Article)

Antibiotic-loaded bone cement has been used since the 1960s, and its advantages in the treatment of existing prosthetic infections have been repeatedly demonstrated. Care should be taken to match the antibiotic to the infecting organism, and cement intended for long-term prosthetic fixation should not contain >2 g of antibiotic powder per 80 g of polymethylmethacrylate. The use of antibiotic-loaded bone cement for prophylaxis against infection is controversial and should be used on an individual risk-benefit basis for patient groups at highest risk for development of deep infection.

Full Text

Duke Authors

Cited Authors

  • Jiranek, W

Published Date

  • August 2005

Published In

Volume / Issue

  • 28 / 8 Suppl

Start / End Page

  • s873 - s877

PubMed ID

  • 16119731

International Standard Serial Number (ISSN)

  • 0147-7447

Digital Object Identifier (DOI)

  • 10.3928/0147-7447-20050802-14


  • eng

Conference Location

  • United States