Irrigation and debridement for periprosthetic infections: Does the organism matter?

Journal Article (Journal Article)

Irrigation and debridement (I&D) is an attractive treatment alternative for periprosthetic joint infection (PJI). Irrigation and debridement failure rates average 64% (range, 10.5%-84%) and may be associated with causative organism type and virulence. The study objective was to compare revision rates for PJI caused by streptococcal organisms to other organisms treated with I&D. A multicenter retrospective cohort study of 200 consecutive PJIs treated with I&D was performed. Failure was defined as reoperation for PJI. Failure rate for streptococcal infections was 65% (20/31) compared with 71% (84/119) for other organisms. Failure rate for sensitive Staphylococcus was 72% (48/67) compared with a 76% (22/29) failure rate for resistant Staphylococcus. These results indicate that eradication rates of I&D for a streptococcal PJI are comparable with other causative organisms. Irrigation and debridement should play a limited role in the PJI treatment algorithm regardless of organism type. © 2011 Elsevier Inc.

Full Text

Duke Authors

Cited Authors

  • Odum, SM; Fehring, TK; Lombardi, AV; Zmistowski, BM; Brown, NM; Luna, JT; Fehring, KA; Hansen, EN; Berend, KR; Bozic, KJ; Valle, CJD; Gioe, TJ; Jiranek, WA; Parvizi, J; Springer, BD

Published Date

  • January 1, 2011

Published In

Volume / Issue

  • 26 / SUPPL. 6

Start / End Page

  • 114 - 118

Electronic International Standard Serial Number (EISSN)

  • 1532-8406

International Standard Serial Number (ISSN)

  • 0883-5403

Digital Object Identifier (DOI)

  • 10.1016/j.arth.2011.03.031

Citation Source

  • Scopus