Review of Recent Methodological Developments in Group-Randomized Trials: Part 1-Design.

Journal Article (Journal Article;Review)

In 2004, Murray et al. reviewed methodological developments in the design and analysis of group-randomized trials (GRTs). We have highlighted the developments of the past 13 years in design with a companion article to focus on developments in analysis. As a pair, these articles update the 2004 review. We have discussed developments in the topics of the earlier review (e.g., clustering, matching, and individually randomized group-treatment trials) and in new topics, including constrained randomization and a range of randomized designs that are alternatives to the standard parallel-arm GRT. These include the stepped-wedge GRT, the pseudocluster randomized trial, and the network-randomized GRT, which, like the parallel-arm GRT, require clustering to be accounted for in both their design and analysis.

Full Text

Duke Authors

Cited Authors

  • Turner, EL; Li, F; Gallis, JA; Prague, M; Murray, DM

Published Date

  • June 2017

Published In

Volume / Issue

  • 107 / 6

Start / End Page

  • 907 - 915

PubMed ID

  • 28426295

Pubmed Central ID

  • PMC5425852

Electronic International Standard Serial Number (EISSN)

  • 1541-0048

Digital Object Identifier (DOI)

  • 10.2105/AJPH.2017.303706


  • eng

Conference Location

  • United States