Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.

Journal Article (Journal Article)

Extracts of involved and uninvolved skin from nine patients with untreated psoriasis were studied for chemotactic activity. Psoriatic plaque contains increased amounts of a complement-dependent chemotactic factor that is inhibited by diisopropyl fluorophosphate. This factor may be human skin serine proteinase.

Full Text

Duke Authors

Cited Authors

  • Lazarus, GS; Yost, FJ; Thomas, CA

Published Date

  • December 16, 1977

Published In

Volume / Issue

  • 198 / 4322

Start / End Page

  • 1162 - 1163

PubMed ID

  • 929193

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.929193


  • eng

Conference Location

  • United States