Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity

Journal Article (Academic article)

A programmable model of membraneless organelles comprised of intrinsically disordered proteins (IDPs) containing sequences of low complexity has now been developed. The rules governing the assembly of archetypal IDPs into biologically inspired mixed, layered and size-controlled configurations provides a new means for understanding intracellular phase behaviour of IDPs.

Full Text

Duke Authors

Cited Authors

  • Simon, JR; Carroll, NJ; Rubinstein, M; Chilkoti, A; López, GP

Published Date

  • 2017

Published In

PubMed ID

  • 28537592

Pubmed Central ID

  • PMC5597244

International Standard Serial Number (ISSN)

  • 1755-4349

Digital Object Identifier (DOI)

  • 10.1038/nchem.2715