Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity
Journal Article (Academic article)
A programmable model of membraneless organelles comprised of intrinsically disordered proteins (IDPs) containing sequences of low complexity has now been developed. The rules governing the assembly of archetypal IDPs into biologically inspired mixed, layered and size-controlled configurations provides a new means for understanding intracellular phase behaviour of IDPs.
Full Text
Duke Authors
Cited Authors
- Simon, JR; Carroll, NJ; Rubinstein, M; Chilkoti, A; López, GP
Published Date
- 2017
Published In
PubMed ID
- 28537592
Pubmed Central ID
- PMC5597244
International Standard Serial Number (ISSN)
- 1755-4349
Digital Object Identifier (DOI)
- 10.1038/nchem.2715