Reliability of the triple-timed up-and-go test.

Journal Article (Journal Article)

INTRODUCTION: We report the reliability of a new measure, the triple-timed up-and-go (3TUG) test, for assessing clinical function in patients with Lambert-Eaton myasthenia (LEM). METHODS: Intrarater reproducibility and interrater agreement of the 3TUG test were assessed in 25 control participants, 24 patients with non-LEM neuromuscular disease, and 12 patients with LEM. The coverage probability (CP) method was the primary measure of reproducibility and agreement. The a priori acceptable range was < 20% difference in 3TUG test times and a CP ≥0.90 confirmed agreement. RESULTS: CP values > 0.90 for intrarater and interrater tests confirmed acceptable reproducibility and agreement for all groups. DISCUSSION: The 3TUG test is a quick, noninvasive, and reproducible measure that is easy to perform, measures clinically important weakness in LEM patients, and requires little training. Additional evaluation in a larger number of LEM patients is in progress to validate the 3TUG test as a clinical measure in LEM. Muscle Nerve 57: 136-139, 2017.

Full Text

Duke Authors

Cited Authors

  • Sanders, DB; Guptill, JT; AleŇ°, KL; Hobson-Webb, LD; Jacobus, DP; Mahmood, R; Massey, JM; Pittman, MM; Prather, K; Raja, SM; Yow, E; Juel, VC

Published Date

  • January 2018

Published In

Volume / Issue

  • 57 / 1

Start / End Page

  • 136 - 139

PubMed ID

  • 28545168

Pubmed Central ID

  • PMC5702274

Electronic International Standard Serial Number (EISSN)

  • 1097-4598

Digital Object Identifier (DOI)

  • 10.1002/mus.25700


  • eng

Conference Location

  • United States