Cellular and Synaptic Properties of Local Inhibitory Circuits.

Journal Article (Journal Article)

Inhibitory interneurons play a key role in sculpting the information processed by neural circuits. Despite the wide range of physiologically and morphologically distinct types of interneurons that have been identified, common principles have emerged that have shed light on how synaptic inhibition operates, both mechanistically and functionally, across cell types and circuits. This introduction summarizes how electrophysiological approaches have been used to illuminate these key principles, including basic interneuron circuit motifs, the functional properties of inhibitory synapses, and the main roles for synaptic inhibition in regulating neural circuit function. It also highlights how some key electrophysiological methods and experiments have advanced our understanding of inhibitory synapse function.

Full Text

Duke Authors

Cited Authors

  • Hull, C

Published Date

  • May 1, 2017

Published In

Volume / Issue

  • 2017 / 5

PubMed ID

  • 28461682

Pubmed Central ID

  • PMC6343672

Electronic International Standard Serial Number (EISSN)

  • 1559-6095

Digital Object Identifier (DOI)

  • 10.1101/pdb.top095281


  • eng

Conference Location

  • United States