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Molecular mechanisms of astrocyte-induced synaptogenesis.

Publication ,  Journal Article
Baldwin, KT; Eroglu, C
Published in: Curr Opin Neurobiol
August 2017

Astrocytes are morphologically complex cells that perform a wide variety of critical functions in the brain. As a structurally and functionally integrated component of the synapse, astrocytes secrete proteins, lipids, and small molecules that bind neuronal receptors to promote synaptogenesis and regulate synaptic connectivity. Additionally, astrocytes are key players in circuit formation, instructing the formation of synapses between distinct classes of neurons. This review highlights recent publications on the topic of astrocyte-mediated synaptogenesis, with a focus on the molecular mechanisms through which astrocytes orchestrate the formation of synaptic circuits.

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Published In

Curr Opin Neurobiol

DOI

EISSN

1873-6882

Publication Date

August 2017

Volume

45

Start / End Page

113 / 120

Location

England

Related Subject Headings

  • Synapses
  • Neurogenesis
  • Humans
  • Brain
  • Astrocytes
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
 

Citation

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Baldwin, K. T., & Eroglu, C. (2017). Molecular mechanisms of astrocyte-induced synaptogenesis. Curr Opin Neurobiol, 45, 113–120. https://doi.org/10.1016/j.conb.2017.05.006
Baldwin, Katherine T., and Cagla Eroglu. “Molecular mechanisms of astrocyte-induced synaptogenesis.Curr Opin Neurobiol 45 (August 2017): 113–20. https://doi.org/10.1016/j.conb.2017.05.006.
Baldwin KT, Eroglu C. Molecular mechanisms of astrocyte-induced synaptogenesis. Curr Opin Neurobiol. 2017 Aug;45:113–20.
Baldwin, Katherine T., and Cagla Eroglu. “Molecular mechanisms of astrocyte-induced synaptogenesis.Curr Opin Neurobiol, vol. 45, Aug. 2017, pp. 113–20. Pubmed, doi:10.1016/j.conb.2017.05.006.
Baldwin KT, Eroglu C. Molecular mechanisms of astrocyte-induced synaptogenesis. Curr Opin Neurobiol. 2017 Aug;45:113–120.
Journal cover image

Published In

Curr Opin Neurobiol

DOI

EISSN

1873-6882

Publication Date

August 2017

Volume

45

Start / End Page

113 / 120

Location

England

Related Subject Headings

  • Synapses
  • Neurogenesis
  • Humans
  • Brain
  • Astrocytes
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences