Emergence of the Molds Other than Aspergillus in Immunocompromised Patients.

Accepted

Journal Article (Review)

Immunocompromised patients are at high risk for invasive fungal infections (IFIs); although Aspergillus remains the most common IFI caused by molds, other fungi, such as Mucorales, dematiaceous molds, and Fusarium spp, are being seen with increasing frequency. Presentations can vary, but sinopulmonary and disseminated infections are common. Our understanding of the pathogenesis of these infections is rudimentary. Fungal cultures and histopathology remain the backbone of diagnostics, as no good serologic markers are available. Polymerase chain reaction tests are being developed but currently remain investigational. Management of these infections is usually multidisciplinary, requiring surgical debridement along with antifungal therapy.

Full Text

Duke Authors

Cited Authors

  • Arif, S; Perfect, JR

Published Date

  • September 2017

Published In

Volume / Issue

  • 38 / 3

Start / End Page

  • 555 - 573

PubMed ID

  • 28797495

Electronic International Standard Serial Number (EISSN)

  • 1557-8216

International Standard Serial Number (ISSN)

  • 0272-5231

Digital Object Identifier (DOI)

  • 10.1016/j.ccm.2017.04.014

Language

  • eng