Neural Correlates of Sensory Hyporesponsiveness in Toddlers at High Risk for Autism Spectrum Disorder.

Published

Journal Article

Altered patterns of sensory responsiveness are a frequently reported feature of Autism Spectrum Disorder (ASD). Younger siblings of individuals with ASD are at a greatly elevated risk of a future diagnosis of ASD, but little is known about the neural basis of sensory responsiveness patterns in this population. Younger siblings (n = 20) of children diagnosed with ASD participated in resting electroencephalography (EEG) at an age of 18 months. Data on toddlers' sensory responsiveness were obtained using the Sensory Experiences Questionnaire. Correlations were present between hyporesponsiveness and patterns of oscillatory power, functional connectivity, and signal complexity. Our findings suggest that neural signal features hold promise for facilitating early identification and targeted remediation in young children at risk for ASD.

Full Text

Cited Authors

  • Simon, DM; Damiano, CR; Woynaroski, TG; Ibañez, LV; Murias, M; Stone, WL; Wallace, MT; Cascio, CJ

Published Date

  • September 2017

Published In

Volume / Issue

  • 47 / 9

Start / End Page

  • 2710 - 2722

PubMed ID

  • 28597185

Pubmed Central ID

  • 28597185

Electronic International Standard Serial Number (EISSN)

  • 1573-3432

International Standard Serial Number (ISSN)

  • 0162-3257

Digital Object Identifier (DOI)

  • 10.1007/s10803-017-3191-4

Language

  • eng