Immunotherapy for Brain Tumors.


Journal Article (Review)

Glioblastoma (GBM) is the most lethal form of brain tumor and remains a large, unmet medical need. This review focuses on recent advances in the neurosciences that converge with the broader field of immuno-oncology. Recent findings in neuroanatomy provide a basis for new approaches of cellular therapies for tumors that involve the CNS. The ultimate success of immunotherapy in the CNS will require improved imaging technologies and methods for analysis of the tumor microenvironment in patients with GBM. It is likely that combinatorial approaches with targeted immunotherapies will be required to exploit the vulnerabilities of GBM and other brain tumors.

Full Text

Duke Authors

Cited Authors

  • Sampson, JH; Maus, MV; June, CH

Published Date

  • July 20, 2017

Published In

Volume / Issue

  • 35 / 21

Start / End Page

  • 2450 - 2456

PubMed ID

  • 28640704

Pubmed Central ID

  • 28640704

Electronic International Standard Serial Number (EISSN)

  • 1527-7755

Digital Object Identifier (DOI)

  • 10.1200/JCO.2017.72.8089


  • eng

Conference Location

  • United States