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A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population.

Publication ,  Journal Article
Randazzo, DM; McSherry, F; Herndon, JE; Affronti, ML; Lipp, ES; Flahiff, C; Miller, E; Woodring, S; Freeman, M; Healy, P; Minchew, J; Keir, S ...
Published in: J Neurooncol
September 2017

Primary brain tumor patients experience high levels of distress. The purpose of this cross-sectional, retrospective study is to evaluate the level and different sources of psychosocial distress and how these pertain to health-related quality of life (HRQoL). The Primary and Recurrent Glioma registry at Duke's The Preston Robert Tisch Brain Tumor Center was queried retrospectively for demographic and clinical information on patients seen between December 2013 and February 2014. Data also included the National Comprehensive Cancer Network's Distress Thermometer (NCCN-DT), Functional Assessment of Cancer Therapy-Brain Cancer (FACT-Br), and Functional Assessment of Chronic Illness Therapy- Fatigue (FACIT-F). 829 subjects completed questionnaires. 54% were male; 96% completed the NCCN-DT; 33.3% had a DT score ≥4 (moderate/severe distress). Women reported DT ≥ 4 more often than men (38.6 vs 29.0%; p = 0.005). Patients within 1 year of diagnosis reported DT ≥ 4 more often than those 1+ years after diagnosis (38.8 vs 30.9%; p = 0.034). 73.0% reported physical problems; the most frequent being fatigue (43.2%) and memory/concentration (40.9%). 42.0% complained of emotional problems with worry (29.4%) and nervousness (22.4%) being the most common. Patients who reported at least one practical, family, emotional or physical problem had significantly lower HRQoL scores (p < 0.001). Primary brain tumor patients experience memory dysfunction, fatigue, nervousness, worry, and financial concerns, which have a negative effect on the patient's HRQoL. By identifying and addressing these stressors, it may be possible to improve patient HRQoL.

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Published In

J Neurooncol

DOI

EISSN

1573-7373

Publication Date

September 2017

Volume

134

Issue

2

Start / End Page

363 / 369

Location

United States

Related Subject Headings

  • Young Adult
  • Time Factors
  • Surveys and Questionnaires
  • Stress, Psychological
  • Sex Factors
  • Retrospective Studies
  • Registries
  • Quality of Life
  • Oncology & Carcinogenesis
  • Middle Aged
 

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Randazzo, D. M., McSherry, F., Herndon, J. E., Affronti, M. L., Lipp, E. S., Flahiff, C., … Peters, K. B. (2017). A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population. J Neurooncol, 134(2), 363–369. https://doi.org/10.1007/s11060-017-2535-4
Randazzo, Dina M., Frances McSherry, James E. Herndon, Mary Lou Affronti, Eric S. Lipp, Charlene Flahiff, Elizabeth Miller, et al. “A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population.J Neurooncol 134, no. 2 (September 2017): 363–69. https://doi.org/10.1007/s11060-017-2535-4.
Randazzo DM, McSherry F, Herndon JE, Affronti ML, Lipp ES, Flahiff C, et al. A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population. J Neurooncol. 2017 Sep;134(2):363–9.
Randazzo, Dina M., et al. “A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population.J Neurooncol, vol. 134, no. 2, Sept. 2017, pp. 363–69. Pubmed, doi:10.1007/s11060-017-2535-4.
Randazzo DM, McSherry F, Herndon JE, Affronti ML, Lipp ES, Flahiff C, Miller E, Woodring S, Freeman M, Healy P, Minchew J, Boulton S, Desjardins A, Vlahovic G, Friedman HS, Keir S, Peters KB. A cross sectional analysis from a single institution's experience of psychosocial distress and health-related quality of life in the primary brain tumor population. J Neurooncol. 2017 Sep;134(2):363–369.
Journal cover image

Published In

J Neurooncol

DOI

EISSN

1573-7373

Publication Date

September 2017

Volume

134

Issue

2

Start / End Page

363 / 369

Location

United States

Related Subject Headings

  • Young Adult
  • Time Factors
  • Surveys and Questionnaires
  • Stress, Psychological
  • Sex Factors
  • Retrospective Studies
  • Registries
  • Quality of Life
  • Oncology & Carcinogenesis
  • Middle Aged