Predictors of the severity of acute pancreatitis in patients with HIV infection or AIDS.

Published

Journal Article

We retrospectively reviewed the charts of 54 human immunodeficiency virus (HIV) infected patients or acquired immunodeficiency syndrome (AIDS), who were hospitalized at the Bronx-Lebanon Hospital Center with acute pancreatitis between January 1993 and December 1995. Nineteen were female and 35 were male patients. Thirty-five (65%) of 54 patients were younger than 40 years (average age, 42 years). Forty-eight (89%) of the patients had a CD4 count of <200 units/ml of blood. Seventeen (32%) patients died either of complications of acute pancreatitis or of underlying disease. The conventional prognostic criteria used to assess the severity of pancreatitis, including Ranson's and Imrie's criteria and the APACHE II system, were applied. We determined that these criteria were not appropriate to our HIV/AIDS patients. Only serum calcium levels at 48 h after admission and serum creatinine and blood urea nitrogen (BUN) at admission and at 48 h after admission had significant p values (<0.05). We believe that the predictors commonly used to identify the severity of pancreatitis were not useful in these patients because of their low CD4 counts and preexisting liver and renal disease.

Full Text

Duke Authors

Cited Authors

  • Parithivel, VS; Yousuf, AM; Albu, E; Kaul, A; Aydinalp, N

Published Date

  • August 1999

Published In

Volume / Issue

  • 19 / 2

Start / End Page

  • 133 - 136

PubMed ID

  • 10438159

Pubmed Central ID

  • 10438159

Electronic International Standard Serial Number (EISSN)

  • 1536-4828

International Standard Serial Number (ISSN)

  • 0885-3177

Digital Object Identifier (DOI)

  • 10.1159/000013439

Language

  • eng