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Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex.

Publication ,  Journal Article
Nallasamy, N; Seider, MI; Gururangan, S; Mruthyunjaya, P
Published in: J AAPOS
August 2017

Retinal astrocytic hamartomas (RAH) are the most frequent ocular manifestation of tuberous sclerosis complex and are usually indolent, requiring only observation. We report an aggressive RAH subtype in a child unresponsive to anti-VEGF and laser therapy. Treatment with systemic everolimus was well-tolerated and significantly reduced ocular (and nonocular) tumor size and fluid exudation.

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Published In

J AAPOS

DOI

EISSN

1528-3933

Publication Date

August 2017

Volume

21

Issue

4

Start / End Page

328 / 331

Location

United States

Related Subject Headings

  • Tuberous Sclerosis
  • TOR Serine-Threonine Kinases
  • Retinal Diseases
  • Ophthalmology & Optometry
  • Male
  • Infant
  • Immunosuppressive Agents
  • Humans
  • Everolimus
  • Drug Administration Schedule
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nallasamy, N., Seider, M. I., Gururangan, S., & Mruthyunjaya, P. (2017). Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex. J AAPOS, 21(4), 328–331. https://doi.org/10.1016/j.jaapos.2017.04.012
Nallasamy, Nambi, Michael I. Seider, Sridharan Gururangan, and Prithvi Mruthyunjaya. “Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex.J AAPOS 21, no. 4 (August 2017): 328–31. https://doi.org/10.1016/j.jaapos.2017.04.012.
Nallasamy N, Seider MI, Gururangan S, Mruthyunjaya P. Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex. J AAPOS. 2017 Aug;21(4):328–31.
Nallasamy, Nambi, et al. “Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex.J AAPOS, vol. 21, no. 4, Aug. 2017, pp. 328–31. Pubmed, doi:10.1016/j.jaapos.2017.04.012.
Nallasamy N, Seider MI, Gururangan S, Mruthyunjaya P. Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex. J AAPOS. 2017 Aug;21(4):328–331.
Journal cover image

Published In

J AAPOS

DOI

EISSN

1528-3933

Publication Date

August 2017

Volume

21

Issue

4

Start / End Page

328 / 331

Location

United States

Related Subject Headings

  • Tuberous Sclerosis
  • TOR Serine-Threonine Kinases
  • Retinal Diseases
  • Ophthalmology & Optometry
  • Male
  • Infant
  • Immunosuppressive Agents
  • Humans
  • Everolimus
  • Drug Administration Schedule