Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex.

Journal Article (Journal Article)

Retinal astrocytic hamartomas (RAH) are the most frequent ocular manifestation of tuberous sclerosis complex and are usually indolent, requiring only observation. We report an aggressive RAH subtype in a child unresponsive to anti-VEGF and laser therapy. Treatment with systemic everolimus was well-tolerated and significantly reduced ocular (and nonocular) tumor size and fluid exudation.

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Duke Authors

Mruthyunjaya, Prithvi

Cited Authors

Nallasamy, N; Seider, MI; Gururangan, S; Mruthyunjaya, P

Published Date

August 2017

Published In

J Aapos

Volume / Issue

21 / 4

Start / End Page

328 - 331

PubMed ID

28733147

Electronic International Standard Serial Number (EISSN)

1528-3933

Digital Object Identifier (DOI)

10.1016/j.jaapos.2017.04.012

Language

Conference Location

United States

Scholars@Duke