Everolimus to treat aggressive retinal astrocytic hamartoma in tuberous sclerosis complex.

Journal Article (Journal Article)

Retinal astrocytic hamartomas (RAH) are the most frequent ocular manifestation of tuberous sclerosis complex and are usually indolent, requiring only observation. We report an aggressive RAH subtype in a child unresponsive to anti-VEGF and laser therapy. Treatment with systemic everolimus was well-tolerated and significantly reduced ocular (and nonocular) tumor size and fluid exudation.

Full Text

Duke Authors

Cited Authors

  • Nallasamy, N; Seider, MI; Gururangan, S; Mruthyunjaya, P

Published Date

  • August 2017

Published In

Volume / Issue

  • 21 / 4

Start / End Page

  • 328 - 331

PubMed ID

  • 28733147

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2017.04.012


  • eng

Conference Location

  • United States