How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?

Published

Conference Paper

© Published under licence by IOP Publishing Ltd. To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MR-compatibility, and energy-independence. An open calibration field and symmetrical 3-field plans were delivered to 10cm diameter PRESAGE® to examine percent depth dose and response uniformity under a magnetic field. Evidence of non-linear dose response led to a large volume PRESAGE® study where small corrections were developed for temporally- and spatially-dependent behaviors observed between irradiation and delayed readout. TG-119 plans were created in the MRIdian® TPS and then delivered to 14.5cm 2kg PRESAGE® dosimeters. Through the domestic investigation of an off-site MRgRT system, a refined 3D remote dosimetry protocol is presented capable of validation of advanced MRgRT radiation treatments.

Full Text

Duke Authors

Cited Authors

  • Mein, S; Rankine, L; Miles, D; Juang, T; Cai, B; Curcuru, A; Mutic, S; Fenoli, J; Adamovics, J; Li, H; Oldham, M

Published Date

  • June 5, 2017

Published In

Volume / Issue

  • 847 / 1

Electronic International Standard Serial Number (EISSN)

  • 1742-6596

International Standard Serial Number (ISSN)

  • 1742-6588

Digital Object Identifier (DOI)

  • 10.1088/1742-6596/847/1/012056

Citation Source

  • Scopus