Interactions of 1263W94 with other antiviral agents in inhibition of human cytomegalovirus replication.

Journal Article

Inhibition of human cytomegalovirus (HCMV) by 1263W94 was additive dosewise in combination with ganciclovir, acyclovir, and foscarnet. None of the commonly used anti-human immunodeficiency virus agents antagonized the inhibition of HCMV by 1263W94. The data were analyzed by a modified isobologram procedure that measures the strength and statistical significance of drug interactions.

Full Text

Duke Authors

Cited Authors

  • Selleseth, DW; Talarico, CL; Miller, T; Lutz, MW; Biron, KK; Harvey, RJ

Published Date

  • April 2003

Published In

Volume / Issue

  • 47 / 4

Start / End Page

  • 1468 - 1471

PubMed ID

  • 12654696

Pubmed Central ID

  • 12654696

International Standard Serial Number (ISSN)

  • 0066-4804

Digital Object Identifier (DOI)

  • 10.1128/aac.47.4.1468-1471.2003

Language

  • eng

Conference Location

  • United States