Comparing oncologic outcomes after minimally invasive and open surgery for pediatric neuroblastoma and Wilms tumor.
Published
Journal Article
BACKGROUND: Minimally invasive surgery (MIS) has been widely adopted for common operations in pediatric surgery; however, its role in childhood tumors is limited by concerns about oncologic outcomes. We compared open and MIS approaches for pediatric neuroblastoma and Wilms tumor (WT) using a national database. METHODS: The National Cancer Data Base from 2010 to 2012 was queried for cases of neuroblastoma and WT in children ≤21 years old. Children were classified as receiving open or MIS surgery for definitive resection, with clinical outcomes compared using a propensity matching methodology (two open:one MIS). RESULTS: For children with neuroblastoma, 17% (98 of 579) underwent MIS, while only 5% of children with WT (35 of 695) had an MIS approach for tumor resection. After propensity matching, there was no difference between open and MIS surgery for either tumor for 30-day mortality, readmissions, surgical margin status, and 1- and 3-year survival. However, in both tumors, open surgery more often evaluated lymph nodes and had larger lymph node harvest. CONCLUSION: Our retrospective review suggests that the use of MIS appears to be a safe method of oncologic resection for select children with neuroblastoma and WT. Further research should clarify which children are the optimal candidates for this approach.
Full Text
Duke Authors
- Adibe, Obinna Ogochukwu
- Ezekian, Brian
- Rice, Henry Elliot
- Routh, Jonathan Charles
- Tracy, Elisabeth Tomlinson
Cited Authors
- Ezekian, B; Englum, BR; Gulack, BC; Rialon, KL; Kim, J; Talbot, LJ; Adibe, OO; Routh, JC; Tracy, ET; Rice, HE
Published Date
- January 2018
Published In
Volume / Issue
- 65 / 1
PubMed ID
- 28792662
Pubmed Central ID
- 28792662
Electronic International Standard Serial Number (EISSN)
- 1545-5017
Digital Object Identifier (DOI)
- 10.1002/pbc.26755
Language
- eng
Conference Location
- United States