The Metabolic Syndrome in Children and Adolescents: Shifting the Focus to Cardiometabolic Risk Factor Clustering.

Published

Journal Article

Metabolic syndrome (MetS) was developed by the National Cholesterol Education Program Adult Treatment Panel III, identifying adults with at least 3 of 5 cardiometabolic risk factors (hyperglycemia, increased central adiposity, elevated triglycerides, decreased high-density lipoprotein cholesterol, and elevated blood pressure) who are at increased risk of diabetes and cardiovascular disease. The constellation of MetS component risk factors has a shared pathophysiology and many common treatment approaches grounded in lifestyle modification. Several attempts have been made to define MetS in the pediatric population. However, in children, the construct is difficult to define and has unclear implications for clinical care. In this Clinical Report, we focus on the importance of screening for and treating the individual risk factor components of MetS. Focusing attention on children with cardiometabolic risk factor clustering is emphasized over the need to define a pediatric MetS.

Full Text

Duke Authors

Cited Authors

  • Magge, SN; Goodman, E; Armstrong, SC; COMMITTEE ON NUTRITION, ; SECTION ON ENDOCRINOLOGY, ; SECTION ON OBESITY,

Published Date

  • August 2017

Published In

Volume / Issue

  • 140 / 2

PubMed ID

  • 28739653

Pubmed Central ID

  • 28739653

Electronic International Standard Serial Number (EISSN)

  • 1098-4275

Digital Object Identifier (DOI)

  • 10.1542/peds.2017-1603

Language

  • eng

Conference Location

  • United States