Advancing clinical trial design in pulmonary hypertension
© 2013, Taylor and Francis Inc. All rights reserved. In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare diseases. A workshop was established to consider alternative clinical trial designs in pulmonary hypertension and here discusses their merits, limitations and challenges to implementation of novel approaches.
Grieve, AP; Chow, SC; Curram, J; Dawe, S; Harnisch, LO; Henig, NR; Hung, HMJ; Ivy, DD; Kawut, SM; Rahbar, MH; Xiao, S; Wilkins, MR
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