Advancing clinical trial design in pulmonary hypertension


Journal Article

© 2013, Taylor and Francis Inc. All rights reserved. In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare diseases. A workshop was established to consider alternative clinical trial designs in pulmonary hypertension and here discusses their merits, limitations and challenges to implementation of novel approaches.

Full Text

Duke Authors

Cited Authors

  • Grieve, AP; Chow, SC; Curram, J; Dawe, S; Harnisch, LO; Henig, NR; Hung, HMJ; Ivy, DD; Kawut, SM; Rahbar, MH; Xiao, S; Wilkins, MR

Published Date

  • January 1, 2013

Published In

Volume / Issue

  • 3 / 1

Start / End Page

  • 217 - 225

Electronic International Standard Serial Number (EISSN)

  • 2045-8940

International Standard Serial Number (ISSN)

  • 2045-8932

Digital Object Identifier (DOI)

  • 10.4103/2045-8932.109933

Citation Source

  • Scopus