OBJECTIVES: To compare male and female radiology faculty publication productivity metrics at four major academic centers. MATERIALS AND METHODS: All Radiology Department faculty members at four academic medical centers from January 1, 2000, to December 31, 2015, were included. Publication metrics including total number of manuscripts published; h- and m-indices; number of publications where faculty member was listed as first, last, or sole author; whether a woman was listed as one of the first five coauthors; and year of first publication were retrieved from Scopus. Publication metrics were compared between genders using the Wilcoxon signed-rank and χ2 tests. RESULTS: A total of 711 faculty members (519 male, 192 [27%] female members) were identified. Male faculty had a significantly higher number of total publications (median 54 versus 24, P < .0001), publications per year (median 2.9 versus 1.6, P < .0001), and h- (median 17 versus 10, P < .0001) and m-indices (median 0.83 versus 0.60, P < .0001) than female faculty. Male faculty had a significantly higher percentage of single author (median 1% versus 0%, P = .0014) and last author (median 16% versus 11%, P < .0001) publications than female faculty. Female faculty had a significantly higher percentage of first author publications (21% versus 17%, P = .0025) and were significantly more likely to have another woman in their first five coauthor list (70% versus 45%, P < .0001) than male faculty. CONCLUSIONS: Large differences exist between female and male faculty in total publications; h- and m-indices; publications per year; number of first, single, last author papers; and percentage of faculty that have a female coauthor in their top five coauthor lists.