Characterization of jet formation and flow field produced by tandem bubbles

Conference Paper

Tandem bubble (TB) interactions have been shown to produce directional jets that can be used to create membrane poration on single cells. Jet speed and associated flow field produced around the TB have been postulated to play an important role in TB-induced bioeffects. In this study, dynamics of tandem bubble interaction in a microfluidic channel (25 μm in height) was analyzed by high-speed imaging and simulated using 3DYNAFS-BEM© (DYNAFLOW, INC.). The results suggest that jet size and geometry are primarily controlled by the maximum diameter of the first bubble (D1) while jet speed is about linearly correlated with maximum diameter of the second bubble (D2).

Full Text

Duke Authors

Cited Authors

  • Yang, C; Koff, AS; Yuan, F; Zhong, P; Hsiao, CT; Chahine, GL

Published Date

  • March 17, 2017

Published In

Volume / Issue

  • 1821 /

Electronic International Standard Serial Number (EISSN)

  • 1551-7616

International Standard Serial Number (ISSN)

  • 0094-243X

International Standard Book Number 13 (ISBN-13)

  • 9780735414891

Digital Object Identifier (DOI)

  • 10.1063/1.4977637

Citation Source

  • Scopus