Portal vein arterialization in hepatobiliary surgery and liver transplantation.


Journal Article

We reviewed the literature reports and our personal experience on partial portal vein arterialization (PPVA) to prevent and treat acute liver failure (ALF) following major hepatobiliary surgery or another etiology. Experimental studies in rats have assessed the efficacy of PPVA in treatment of ALF induced by extended resections in normal or fatty livers or in toxic carbon-tetrachloride damage. The treated groups showed greater survival and faster recovery of liver function. Among 11 clinical cases reported in the literature, PPVA was performed in four cases to prevent and in seven cases to treat ALF. Eight patients survived, showing rapid recovery of liver function and resolution of the clinical condition. This relatively simple procedure has shown itself able to promote liver regeneration. The PPVA procedure has shown itself to be safe and simple as well as to offer a promising approach to the failing liver.

Full Text

Cited Authors

  • Tsivian, M; Neri, F; Prezzi, D; Puviani, L; Pacile, V; Bertelli, R; Cavallari, G; Mattioli, B; Bianchi, E; Piras, GL; Pariali, M; Nardo, B

Published Date

  • July 2007

Published In

Volume / Issue

  • 39 / 6

Start / End Page

  • 1877 - 1878

PubMed ID

  • 17692639

Pubmed Central ID

  • 17692639

International Standard Serial Number (ISSN)

  • 0041-1345

Digital Object Identifier (DOI)

  • 10.1016/j.transproceed.2007.05.058


  • eng

Conference Location

  • United States