Epidural spinal involvement of Erdheim-Chester disease causing myelopathy.

Journal Article (Journal Article)

We present a 25-year-old woman with Erdheim-Chester disease (ECD) presenting with progressive myelopathy from multiple compressive spinal epidural lesions who required cervicothoracic decompression and fusion, and summarize the literature on epidural spinal involvement of ECD. ECD is a rare non-Langerhans histiocytosis affecting multiple organ systems through infiltration and characteristically causing multifocal osteosclerosis. Central nervous system involvement, particularly of the spine, is rare.

Full Text

Duke Authors

Cited Authors

  • Hwang, BY; Liu, A; Kern, J; Goodwin, CR; Wolinsky, JP; Desai, A

Published Date

  • September 2015

Published In

Volume / Issue

  • 22 / 9

Start / End Page

  • 1532 - 1536

PubMed ID

  • 26119978

Electronic International Standard Serial Number (EISSN)

  • 1532-2653

Digital Object Identifier (DOI)

  • 10.1016/j.jocn.2015.04.004


  • eng

Conference Location

  • Scotland