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Non-hepatocellular carcinoma spinal metastases.

Publication ,  Journal Article
Goodwin, CR; Abu-Bonsrah, N; Boone, C; Ruiz-Valls, A; Sankey, EW; Sarabia-Estrada, R; Elder, BD; Kosztowski, T; Sciubba, DM
Published in: J Clin Neurosci
May 2016

Metastases to the spine from non-hepatocellular carcinomas, such as cholangiocarcinoma and angiosarcoma, occur rarely. With improvements in oncologic care, the number of patients diagnosed with metastatic cancer is expected to increase. We performed a systematic review of the literature to assess the clinical presentation, treatment, outcome and survival of patients diagnosed with non-hepatocellular carcinoma spinal metastasis using PubMed, Embase, CINAHL, Cochrane Library and Web of Science. We identified 19 cases of spinal metastases from non-hepatocellular carcinomas that fit our pre-specified criteria. The mean age at presentation was 62.3years and cholangiocarcinoma was the most common subtype. Patients frequently presented with pain, weakness or paraparesis and at the time of diagnosis, most of them had multi-level involvement of the spine. A majority of patients with spinal metastasis were treated either with radiation or chemotherapy or received no treatment. A minority of the reports included information on survival, which revealed a median survival of 1.5months following diagnosis of the spinal metastasis. Although there is a paucity of published literature on non-hepatocellular carcinoma spinal metastasis, this systematic review provides descriptive clinical characteristics of these patients.

Duke Scholars

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

May 2016

Volume

27

Start / End Page

22 / 27

Location

Scotland

Related Subject Headings

  • Spinal Neoplasms
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Humans
  • Hemangiosarcoma
  • Female
  • Aged
  • 5202 Biological psychology
 

Citation

APA
Chicago
ICMJE
MLA
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Goodwin, C. R., Abu-Bonsrah, N., Boone, C., Ruiz-Valls, A., Sankey, E. W., Sarabia-Estrada, R., … Sciubba, D. M. (2016). Non-hepatocellular carcinoma spinal metastases. J Clin Neurosci, 27, 22–27. https://doi.org/10.1016/j.jocn.2015.11.003
Goodwin, C Rory, Nancy Abu-Bonsrah, Christine Boone, Alejandro Ruiz-Valls, Eric W. Sankey, Rachel Sarabia-Estrada, Benjamin D. Elder, Thomas Kosztowski, and Daniel M. Sciubba. “Non-hepatocellular carcinoma spinal metastases.J Clin Neurosci 27 (May 2016): 22–27. https://doi.org/10.1016/j.jocn.2015.11.003.
Goodwin CR, Abu-Bonsrah N, Boone C, Ruiz-Valls A, Sankey EW, Sarabia-Estrada R, et al. Non-hepatocellular carcinoma spinal metastases. J Clin Neurosci. 2016 May;27:22–7.
Goodwin, C. Rory, et al. “Non-hepatocellular carcinoma spinal metastases.J Clin Neurosci, vol. 27, May 2016, pp. 22–27. Pubmed, doi:10.1016/j.jocn.2015.11.003.
Goodwin CR, Abu-Bonsrah N, Boone C, Ruiz-Valls A, Sankey EW, Sarabia-Estrada R, Elder BD, Kosztowski T, Sciubba DM. Non-hepatocellular carcinoma spinal metastases. J Clin Neurosci. 2016 May;27:22–27.
Journal cover image

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

May 2016

Volume

27

Start / End Page

22 / 27

Location

Scotland

Related Subject Headings

  • Spinal Neoplasms
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Liver Neoplasms
  • Humans
  • Hemangiosarcoma
  • Female
  • Aged
  • 5202 Biological psychology