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A systematic review of the use of expandable cages in the cervical spine.

Publication ,  Journal Article
Elder, BD; Lo, S-F; Kosztowski, TA; Goodwin, CR; Lina, IA; Locke, JE; Witham, TF
Published in: Neurosurg Rev
January 2016

Expandable vertebral body replacement cages (VBRs) have been widely used for reconstruction of the thoracolumbar spine following corpectomy. However, their use in the cervical spine is less common, and currently, no expandable cages on the market are cleared or approved by the US Food and Drug Administration for use in the cervical spine. The objective of this study was to perform a systematic review on the use of expandable cages in the treatment of cervical spine pathology with a focus on fusion rates, deformity correction, complications, and indications. A comprehensive Medline search was performed, and 24 applicable articles were identified and included in this review. The advantages of expandable cages include greater ease of implantation with less risk of damage to the end plate, less intraoperative manipulation of the device, and potentially greater control over lordosis. They may be particularly advantageous in cases with poor bone quality, such as patients with osteoporosis or metastatic tumors that have been radiated. However, there is a potential risk of overdistraction, which is increased in the cervical spine, their minimum height limits their use in cases with collapsed vertebra, and the amount of hardware in the expansion mechanism may limit the surface area available for fusion. The use of expandable VBRs are a valuable tool in the armamentarium for reconstruction of the anterior column of the cervical spine with an acceptable safety profile. Although expandable cervical cages are clearly beneficial in certain clinical situations, widespread use following all corpectomies is not justified due to their significantly greater cost compared to structural bone grafts or non-expandable VBRs, which can be utilized to achieve similar clinical outcomes.

Duke Scholars

Published In

Neurosurg Rev

DOI

EISSN

1437-2320

Publication Date

January 2016

Volume

39

Issue

1

Start / End Page

1 / 11

Location

Germany

Related Subject Headings

  • Spinal Fusion
  • Neurosurgical Procedures
  • Neurology & Neurosurgery
  • Internal Fixators
  • Humans
  • Diffusion Chambers, Culture
  • Cervical Vertebrae
  • 3209 Neurosciences
  • 3203 Dentistry
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Elder, B. D., Lo, S.-F., Kosztowski, T. A., Goodwin, C. R., Lina, I. A., Locke, J. E., & Witham, T. F. (2016). A systematic review of the use of expandable cages in the cervical spine. Neurosurg Rev, 39(1), 1–11. https://doi.org/10.1007/s10143-015-0649-8
Elder, Benjamin D., Sheng-Fu Lo, Thomas A. Kosztowski, C Rory Goodwin, Ioan A. Lina, John E. Locke, and Timothy F. Witham. “A systematic review of the use of expandable cages in the cervical spine.Neurosurg Rev 39, no. 1 (January 2016): 1–11. https://doi.org/10.1007/s10143-015-0649-8.
Elder BD, Lo S-F, Kosztowski TA, Goodwin CR, Lina IA, Locke JE, et al. A systematic review of the use of expandable cages in the cervical spine. Neurosurg Rev. 2016 Jan;39(1):1–11.
Elder, Benjamin D., et al. “A systematic review of the use of expandable cages in the cervical spine.Neurosurg Rev, vol. 39, no. 1, Jan. 2016, pp. 1–11. Pubmed, doi:10.1007/s10143-015-0649-8.
Elder BD, Lo S-F, Kosztowski TA, Goodwin CR, Lina IA, Locke JE, Witham TF. A systematic review of the use of expandable cages in the cervical spine. Neurosurg Rev. 2016 Jan;39(1):1–11.
Journal cover image

Published In

Neurosurg Rev

DOI

EISSN

1437-2320

Publication Date

January 2016

Volume

39

Issue

1

Start / End Page

1 / 11

Location

Germany

Related Subject Headings

  • Spinal Fusion
  • Neurosurgical Procedures
  • Neurology & Neurosurgery
  • Internal Fixators
  • Humans
  • Diffusion Chambers, Culture
  • Cervical Vertebrae
  • 3209 Neurosciences
  • 3203 Dentistry
  • 3202 Clinical sciences