Infiltrating spinal cord astrocytomas: Epidemiology, diagnosis, treatments and future directions.

Journal Article (Journal Article;Review)

Spinal cord gliomas, consisting mostly of ependymomas and astrocytomas, are rare entities. Of the gliomas, infiltrating astrocytomas are particularly challenging entities to treat due to their invasive nature. Surgical resection is oftentimes not possible without subjecting patients to permanent neurological deficits because of the difficulty in establishing clear tissue planes. As more is learned about the molecular genetics, genomics, and biology of these tumors, it is becoming more apparent that there are important differences between these tumors and their more common intracranial counterparts. There also appears to be important clinical differences between low-grade and high-grade astrocytomas. A multidisciplinary approach is needed to optimize the treatment of these difficult tumors.

Full Text

Duke Authors

Cited Authors

  • Abd-El-Barr, MM; Huang, KT; Chi, JH

Published Date

  • July 2016

Published In

Volume / Issue

  • 29 /

Start / End Page

  • 15 - 20

PubMed ID

  • 26944214

Electronic International Standard Serial Number (EISSN)

  • 1532-2653

Digital Object Identifier (DOI)

  • 10.1016/j.jocn.2015.10.048


  • eng

Conference Location

  • Scotland