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Vagus nerve stimulation for drop attacks in a pediatric population.

Publication ,  Journal Article
Abd-El-Barr, MM; Joseph, JR; Schultz, R; Edmonds, JL; Wilfong, AA; Yoshor, D
Published in: Epilepsy Behav
November 2010

A retrospective analysis of 43 patients with drop attack seizures who were treated with vagus nerve stimulation (VNS) was undertaken to determine the efficacy of VNS and to determine pre-implantation characteristics associated with VNS success. It was found that on last follow-up, 46% of patients had at least a 75% reduction in drops per day. Forty-six percent of patients had less than a 50% reduction in drops per day and were considered nonresponders. Univariate analysis failed to uncover significant associations between pre-implantation characteristics and VNS success. It was found that atonic head nods were more amenable to VNS treatment as compared with atonic or tonic drop attacks. In addition, patients with focal or lateralized epileptiform abnormalities responded better to VNS compared with those with more diffuse or poorly localized findings on ictal and/or interictal recordings. Our data suggest that VNS offers significant palliative benefit to many children with medically intractable drop attack seizures.

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Published In

Epilepsy Behav

DOI

EISSN

1525-5069

Publication Date

November 2010

Volume

19

Issue

3

Start / End Page

394 / 399

Location

United States

Related Subject Headings

  • Vagus Nerve Stimulation
  • Treatment Outcome
  • Time Factors
  • Syncope
  • Retrospective Studies
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Follow-Up Studies
 

Citation

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Abd-El-Barr, M. M., Joseph, J. R., Schultz, R., Edmonds, J. L., Wilfong, A. A., & Yoshor, D. (2010). Vagus nerve stimulation for drop attacks in a pediatric population. Epilepsy Behav, 19(3), 394–399. https://doi.org/10.1016/j.yebeh.2010.06.044
Abd-El-Barr, Muhammad M., Jacob R. Joseph, Rebecca Schultz, Joseph L. Edmonds, Angus A. Wilfong, and Daniel Yoshor. “Vagus nerve stimulation for drop attacks in a pediatric population.Epilepsy Behav 19, no. 3 (November 2010): 394–99. https://doi.org/10.1016/j.yebeh.2010.06.044.
Abd-El-Barr MM, Joseph JR, Schultz R, Edmonds JL, Wilfong AA, Yoshor D. Vagus nerve stimulation for drop attacks in a pediatric population. Epilepsy Behav. 2010 Nov;19(3):394–9.
Abd-El-Barr, Muhammad M., et al. “Vagus nerve stimulation for drop attacks in a pediatric population.Epilepsy Behav, vol. 19, no. 3, Nov. 2010, pp. 394–99. Pubmed, doi:10.1016/j.yebeh.2010.06.044.
Abd-El-Barr MM, Joseph JR, Schultz R, Edmonds JL, Wilfong AA, Yoshor D. Vagus nerve stimulation for drop attacks in a pediatric population. Epilepsy Behav. 2010 Nov;19(3):394–399.
Journal cover image

Published In

Epilepsy Behav

DOI

EISSN

1525-5069

Publication Date

November 2010

Volume

19

Issue

3

Start / End Page

394 / 399

Location

United States

Related Subject Headings

  • Vagus Nerve Stimulation
  • Treatment Outcome
  • Time Factors
  • Syncope
  • Retrospective Studies
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Follow-Up Studies