Investigational therapies for brain metastases.

Journal Article (Journal Article;Review)

Contrary to the incidence of primary cancers, the incidence of brain metastasis has been increasing. This increase is likely because of the effects of an aging population, improved neuroimaging surveillance, and better control of systemic cancer, allowing time for brain metastasis to occur. Unlike systemic cancers, for which chemotherapy is the mainstay of treatment, the therapeutic strategies available to treat brain metastasis have traditionally been limited to surgical resection, whole brain radiation therapy, or stereotactic radiosurgery, either individually or in combination. It is important to put the treatment in the context of the prognosis for patients with brain metastases.

Full Text

Duke Authors

Cited Authors

  • Abd-El-Barr, MM; Rahman, M; Rao, G

Published Date

  • January 2011

Published In

Volume / Issue

  • 22 / 1

Start / End Page

  • 87 - vii

PubMed ID

  • 21109153

Electronic International Standard Serial Number (EISSN)

  • 1558-1349

Digital Object Identifier (DOI)

  • 10.1016/


  • eng

Conference Location

  • United States