Orthostatic Hypotension in Patients With Left Ventricular Assist Devices: Acquired Autonomic Dysfunction.

Journal Article (Journal Article)

Contemporary left ventricular assist device (LVAD) technology uses nonphysiologic continuous flow to deliver blood into the circulation. This results in a reduction of pulsatility, which is implicated in some of the commonly associated side effects with LVAD therapy, including hypertension and gastrointestinal arterial-venous malformation with related bleeding. A less frequently observed side effect is orthostatic hypotension (OH) in patients supported with LVAD therapy. We present three cases of OH in patients with LVAD, followed by a discussion on how LVAD therapy may induce autonomic dysfunction.

Full Text

Duke Authors

Cited Authors

  • Fudim, M; Rogers, JG; Frazier-Mills, C; Patel, CB

Published Date

  • 2018

Published In

Volume / Issue

  • 64 / 3

Start / End Page

  • e40 - e42

PubMed ID

  • 28799950

Pubmed Central ID

  • PMC5990041

Electronic International Standard Serial Number (EISSN)

  • 1538-943X

Digital Object Identifier (DOI)

  • 10.1097/MAT.0000000000000640


  • eng

Conference Location

  • United States