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Breast dose reduction with organ-based, wide-angle tube current modulated CT.

Publication ,  Journal Article
Fu, W; Sturgeon, GM; Agasthya, G; Segars, WP; Kapadia, AJ; Samei, E
Published in: J Med Imaging (Bellingham)
July 2017

This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic computed tomography (CT) with a wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT) were used to create a virtual patient population with clinical anatomic variations. The phantoms were created based on patient images with normal anatomy (age range: 27 to 66 years, weight range: 52.0 to 105.8 kg). For each phantom, two breast tissue compositions were simulated: [Formula: see text] and [Formula: see text] (glandular-to-adipose ratio). A validated Monte Carlo program (PENELOPE, Universitat de Barcelona, Spain) was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) using a typical clinical thoracic CT protocol. Both organ dose and [Formula: see text]-to-organ dose conversion coefficients ([Formula: see text] factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses ([Formula: see text]). The breast dose was reduced by [Formula: see text]. For [Formula: see text] factors, organs in the anterior region (e.g., thyroid and stomach) exhibited substantial decreases, and the medial, distributed, and posterior region saw either an increase of less than 5% or no significant change. ODM significantly reduced organ doses especially for radiosensitive superficial anterior organs such as the breasts.

Duke Scholars

Published In

J Med Imaging (Bellingham)

DOI

ISSN

2329-4302

Publication Date

July 2017

Volume

4

Issue

3

Start / End Page

031208

Location

United States

Related Subject Headings

  • 4003 Biomedical engineering
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fu, W., Sturgeon, G. M., Agasthya, G., Segars, W. P., Kapadia, A. J., & Samei, E. (2017). Breast dose reduction with organ-based, wide-angle tube current modulated CT. J Med Imaging (Bellingham), 4(3), 031208. https://doi.org/10.1117/1.JMI.4.3.031208
Fu, Wanyi, Gregory M. Sturgeon, Greeshma Agasthya, William Paul Segars, Anuj J. Kapadia, and Ehsan Samei. “Breast dose reduction with organ-based, wide-angle tube current modulated CT.J Med Imaging (Bellingham) 4, no. 3 (July 2017): 031208. https://doi.org/10.1117/1.JMI.4.3.031208.
Fu W, Sturgeon GM, Agasthya G, Segars WP, Kapadia AJ, Samei E. Breast dose reduction with organ-based, wide-angle tube current modulated CT. J Med Imaging (Bellingham). 2017 Jul;4(3):031208.
Fu, Wanyi, et al. “Breast dose reduction with organ-based, wide-angle tube current modulated CT.J Med Imaging (Bellingham), vol. 4, no. 3, July 2017, p. 031208. Pubmed, doi:10.1117/1.JMI.4.3.031208.
Fu W, Sturgeon GM, Agasthya G, Segars WP, Kapadia AJ, Samei E. Breast dose reduction with organ-based, wide-angle tube current modulated CT. J Med Imaging (Bellingham). 2017 Jul;4(3):031208.

Published In

J Med Imaging (Bellingham)

DOI

ISSN

2329-4302

Publication Date

July 2017

Volume

4

Issue

3

Start / End Page

031208

Location

United States

Related Subject Headings

  • 4003 Biomedical engineering
  • 3202 Clinical sciences