Esophageal Perforation: A Common Clinical Problem with Many Different Management Options.


Journal Article

Esophageal perforation is a complex clinical entity that has multiple etiologies and variability in presentation, making it challenging to diagnose and treat. The mortality of esophageal perforation has improved because therapies have evolved. Whereas primary repair is the standard of care, multiple treatments may be employed successfully. We retrospectively reviewed all cases of suspected or confirmed esophageal perforation that were admitted to the thoracic surgery service at our institution between January 2011 and June 2016. We reviewed the charts of 61 patients. Twenty-three underwent primary repair, 13 underwent stent placement, 12 underwent drainage, 12 underwent medical management, and one underwent exclusion and diversion. All patients were included in the final analysis except the singular patient who underwent diversion. Overall mortality was 4.9 per cent. None of the studied variables were found to be associated with mortality (P > 0.05). Factors associated with choice of treatment were age (P < 0.0005), Charlson Index (P = 0.032), etiology (P < 0.0005), and location (P = 0.005). The application of different management options is based on a thorough understanding time course, patient anatomy, severity of presentation, and underlying disease process.

Full Text

Duke Authors

Cited Authors

  • Felmly, LM; Kwon, H; Denlinger, CE; Klapper, JA

Published Date

  • August 1, 2017

Published In

Volume / Issue

  • 83 / 8

Start / End Page

  • 911 - 917

PubMed ID

  • 28822401

Pubmed Central ID

  • 28822401

Electronic International Standard Serial Number (EISSN)

  • 1555-9823


  • eng

Conference Location

  • United States