Skip to main content
Journal cover image

Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses.

Publication ,  Journal Article
Clark-Snow, R; Affronti, ML; Rittenberg, CN
Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
February 2018

Chemotherapy-induced nausea and vomiting (CINV) can be prevented in most patients with use of guideline-recommended antiemetic regimens. However, studies have suggested that adherence to antiemetic guidelines is suboptimal. Oncology nurses, as part of a multidisciplinary team, can help promote appropriate antiemetic prophylaxis. Therefore, nurses were surveyed to assess antiemetic guideline awareness and practice patterns of antiemetic use, determine adherence to guideline recommendations, and query barriers to adherence.In September 2015, 531 US-based oncology nurses participated in an online survey administered and analyzed by ONS:Edge.Nurses were most familiar with National Comprehensive Cancer Network (73%) and American Society of Clinical Oncology (48%) antiemetic guidelines. While most (77%) felt that antiemetics prescribed were consistent with guideline recommendations, practice patterns of antiemetic use revealed low adherence to those guidelines, particularly during the delayed (25-120 h) phase following highly emetogenic chemotherapy, where only 25% of nurses reported administration of guideline-recommended agents. Overutilization of phenothiazines and benzodiazepines was common. Only 17% of respondents reported that most (> 75%) of their patients have CINV optimally controlled; 39% reported between 6 and 20% of patients have an alteration in their chemotherapy due to CINV, and reports of emergency department/hospital visits due to poorly controlled CINV were high. The predominant barrier interfering guideline-recommended antiemetic prophylaxis was reported as physician preference (71%).This survey revealed an opportunity to increase awareness of antiemetic guidelines and a critical need to address barriers interfering with utilization of guideline-recommended antiemetic agents in order to optimize CINV control for patients undergoing emetogenic chemotherapy.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

DOI

EISSN

1433-7339

ISSN

0941-4355

Publication Date

February 2018

Volume

26

Issue

2

Start / End Page

557 / 564

Related Subject Headings

  • Vomiting
  • Surveys and Questionnaires
  • Oncology & Carcinogenesis
  • Nurse Clinicians
  • Nausea
  • Medication Adherence
  • Male
  • Induction Chemotherapy
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Clark-Snow, R., Affronti, M. L., & Rittenberg, C. N. (2018). Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer, 26(2), 557–564. https://doi.org/10.1007/s00520-017-3866-6
Clark-Snow, Rebecca, Mary Lou Affronti, and Cynthia N. Rittenberg. “Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses.Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer 26, no. 2 (February 2018): 557–64. https://doi.org/10.1007/s00520-017-3866-6.
Clark-Snow R, Affronti ML, Rittenberg CN. Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2018 Feb;26(2):557–64.
Clark-Snow, Rebecca, et al. “Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses.Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer, vol. 26, no. 2, Feb. 2018, pp. 557–64. Epmc, doi:10.1007/s00520-017-3866-6.
Clark-Snow R, Affronti ML, Rittenberg CN. Chemotherapy-induced nausea and vomiting (CINV) and adherence to antiemetic guidelines: results of a survey of oncology nurses. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2018 Feb;26(2):557–564.
Journal cover image

Published In

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

DOI

EISSN

1433-7339

ISSN

0941-4355

Publication Date

February 2018

Volume

26

Issue

2

Start / End Page

557 / 564

Related Subject Headings

  • Vomiting
  • Surveys and Questionnaires
  • Oncology & Carcinogenesis
  • Nurse Clinicians
  • Nausea
  • Medication Adherence
  • Male
  • Induction Chemotherapy
  • Humans
  • Female