Regeneration Genetics.

Journal Article (Journal Article;Review)

Understanding how and why animals regenerate complex tissues has the potential to transform regenerative medicine. Here we present an overview of genetic approaches that have recently been applied to dissect mechanisms of regeneration. We describe new advances that relate to central objectives of regeneration biologists researching different tissues and species, focusing mainly on vertebrates. These objectives include defining the cellular sources and key cell behaviors in regenerating tissue, elucidating molecular triggers and brakes for regeneration, and defining the earliest events that control the presence of these molecular factors.

Full Text

Duke Authors

Cited Authors

  • Chen, C-H; Poss, KD

Published Date

  • November 27, 2017

Published In

Volume / Issue

  • 51 /

Start / End Page

  • 63 - 82

PubMed ID

  • 28853919

Pubmed Central ID

  • PMC5705327

Electronic International Standard Serial Number (EISSN)

  • 1545-2948

Digital Object Identifier (DOI)

  • 10.1146/annurev-genet-120116-024554


  • eng

Conference Location

  • United States